Male Rat Susceptibility for Liver and Kidney Injury

Hamad, Sarkawt and Othman, Karwan and Hamad, Karwan and Rasul, Balkes and Abdulla, Shorsh and Ismael, Ismael (2016) Male Rat Susceptibility for Liver and Kidney Injury. ARO-The Scientific Journal of Koya University, 4 (1). pp. 13-16. ISSN 24109355

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Official URL: http://doi.org/10.14500/aro.10087

Abstract

The experimental study of this paper was designed to investigate male rat susceptibility to liver injury. A combination of two experimental animal models (Lead acetate for tissue injury (80 mg / L) and castration) had been used on twenty male rats, they were divided into two groups sham (n = 10); castrated (n = 10). Results revealed that, liver weight reduced significantly (P < 0.05) in sham group in comparison with castrated rats, but kidney weight changed slightly. Also, serum aminotransferase (AST) was significantly higher in sham versus castrated rats. Neither alanine aminotransferase (ALT) and alkaline phosphatase (ALP) nor malondialdehyde (MDA) changed. In conclusion, the absence of male sex hormone would delay tissue injury of male rat organs especially liver organ.

Item Type: Article
Uncontrolled Keywords: Alanine aminotransferase, liver injury, testosterone
Subjects: Q Science > QR Microbiology
Divisions: Aro-The Scientific Journal of Koya University > VOL 4, NO 1 (2016)
Faculty of Science and Health > Department of Biology
Depositing User: ePrints Administrator
Date Deposited: 04 Aug 2016 15:26
Last Modified: 09 Feb 2017 12:26
URI: http://eprints.koyauniversity.org/id/eprint/6

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